10/15/24
USP Chapter <86> Bacterial Endotoxins Test Using Recombinant Reagents: A Step Forward, But Not a Milestone for Horseshoe Crab Conservation
Global: White paper by Glenn Gauvry, founder and president of ERDG. The recent introduction of USP Chapter <86> marks a significant step by incorporating recombinant reagents as alternatives to those derived from horseshoe crab hemolymph in bacterial endotoxin testing. While this advancement reduces reliance on horseshoe crabs, this paper explores why it may not substantially impact the conservation of these species. Major threats like habitat loss, unregulated harvesting in Asia, and other human activities persist. We examine global regulatory landscapes and industry adoption barriers, highlighting the need for continued collaborative efforts to address the broader conservation challenges facing the world’s four horseshoe crab species. USP_Chapter_86_Gauvry_10:14:2024